This cross-sectional study examines discrepancies between registered protocols and subsequent publications for drug and diet trials whose findings were published in prominent clinical journals in the last decade. ClinicalTrials.gov was established in …
Undisclosed discrepancies often exist between study registrations and their associated publications. Discrepancies can increase risk of bias, and when undisclosed, they disguise this increased risk of bias from readers. To remedy this issue, we …
Objectives To identify and appraise empirical studies on publication and related biases published since 1998; to assess methods to deal with publication and related biases; and to examine, in a random sample of published systematic reviews, measures …
This is a collection of research methodology articles, which are first- or senior-authored by women, to promote diverse perspectives in teaching students about research methods and contributing to improving research practices.
Scientists and funding agencies invest considerable resources in writing and evaluating grant proposals. But do grant proposal texts noticeably change panel decisions in single blind review? We report on a field experiment conducted by The Dutch …
Research resources like transgenic animals and antibodies are the workhorses of biomedicine, enabling investigators to relatively easily study specific disease conditions. As key biological resources, transgenic animals and antibodies are often …
Several researchers have recently argued that p values lose their meaning in exploratory analyses due to an unknown inflation of the alpha level (e.g., Nosek & Lakens, 2014; Wagenmakers, 2016). For this argument to be tenable, the familywise error …
Scholars assert that pre-analysis plans (PAPs) generate boring, lab-report style papers and thus hamper publication. We test this claim by comparing the publication rates of experimental NBER working papers with and without PAPs. We find that …
Randomized controlled trials (RCTs) are increasingly prominent in economics, with pre-registration and pre-analysis plans (PAPs) promoted as important in ensuring the credibility of findings. We investigate whether these tools reduce the extent of …