Resources

The case of clinical trials for convalescent plasma during COVID-19 illustrates important lessons for realizing public sector approaches to biomedical research and development. These lessons, centering on mission, transparency, and spillover effects, …

Advancing scientific discovery requires investigators to embrace research practices that increase transparency and disclosure about materials, methods, and outcomes. Several research advocacy and funding organizations have produced guidelines and …

Real-world evidence (RWE) studies are increasingly used to inform policy and clinical decisions. However, there remain concerns about the credibility and reproducibility of RWE studies. While there is universal agreement on the critical importance of …

Campbell’s Law explains the replication crisis. In brief, useful tools such as hypotheses, p-values, and multi-study designs came to be viewed as indicators of strong science, and thus goals in and of themselves. Consequently, their use became …

The biomedical sciences must maintain and enhance a research culture that prioritizes rigour and transparency. The US National Institute of Neurological Disorders and Stroke convened a workshop entitled ‘Catalyzing Communities of Research Rigor …

Open Science practices are integral to increasing transparency, reproducibility, and accessibility of research in health psychology and behavioral medicine. Drives to facilitate Open Science practices are becoming increasingly evident in journal …

Scientists and funding agencies invest considerable resources in writing and evaluating grant proposals. But do grant proposal texts noticeably change panel decisions in single blind review? We report on a field experiment conducted by The Dutch …

The National Academies hosted a hybrid public workshop in Fall 2023, sponsored by the National Institutes of Health, to explore approaches that U.S. Department of Health and Human Services (HHS) agencies could consider as they develop or update …

Efforts by governments, firms, and patients to deliver pioneering drugs for critical health needs face a challenge of diminishing efficiency in developing those medicines. While multi-sectoral collaborations involving firms, researchers, patients, …

Academic institutions have made significant investments to support public access to research data requirements, yet little to no data about these services, infrastructure, and costs currently exist or are widely shared. For public access to research …