Context Most medical interventions have modest effects, but occasionally some clinical trials may find very large effects for benefits or harms. Objective To evaluate the frequency and features of very large effects in medicine. Data Sources Cochrane …
Background Many journals now require authors share their data with other investigators, either by depositing the data in a public repository or making it freely available upon request. These policies are explicit, but remain largely untested. We …
As scientific investigations increasingly adopt Open Science practices, reuse of data becomes paramount. However, despite decades of progress in internet search tools, finding relevant astrobiology datasets for an envisioned investigation remains …
The psychological and psychiatric communities are generating data on an ever-increasing scale. To ensure that society reaps the greatest utility in research and clinical care from such rich resources, there is significant interest in wide-scale, open …
Objectives
This study evaluates the endorsement of open science practices by dental journals.
Materials and methods
This was a meta-research study that included journals listed in the 2021 Journal Citation Reports under Dentistry. A comprehensive …
The National Academies hosted a hybrid public workshop in Fall 2023, sponsored by the National Institutes of Health, to explore approaches that U.S. Department of Health and Human Services (HHS) agencies could consider as they develop or update …
The information provided on this website is designed to assist the extramural community in addressing rigor and transparency in NIH grant applications and progress reports. Scientific rigor and transparency in conducting biomedical research is key to …
The purpose of this paper is to extend to the field of relationship science, recent discussions and suggested changes in open research practises. We demonstrate different ways that greater transparency of the research process in our field will …
Motivation
The maturation of systems immunology methodologies requires novel and transparent computational frameworks capable of integrating diverse data modalities in a reproducible manner.
Results
Here, we present the ePlatypus computational …
Knowledge is essential to saving lives and improving wellbeing. The term open science has been applied to improving the transparency of knowledge generation, but open science also has the potential to address many of the problems of inequity, …