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Characteristics of Clinical Trials Registered in ClinicalTrials.gov, 2007-2010

Context Recent reports highlight gaps between guidelines-based treatment recommendations and evidence from clinical trials that supports those recommendations. Strengthened reporting requirements for studies registered with ClinicalTrials.gov enable …

Experimentation and manipulation with preregistration

Preregistration requires scientists to describe the planned research activities before their project begins. Preregistration improves transparency in empirical research and is an institutional response to scientific misconduct. This paper studies the …

Increasing value and reducing waste: addressing inaccessible research

The methods and results of health research are documented in study protocols, full study reports (detailing all analyses), journal reports, and participant-level datasets. However, protocols, full study reports, and participant-level datasets are …

Preregistration specificity & adherence: A review of preregistered gambling studies & cross-disciplinary comparison

Study preregistration is one of several “open science” practices (e.g., open data, preprints) that researchers use to improve the transparency and rigour of their research. As more researchers adopt preregistration as a regular research practice, …

Publication of NIH funded trials registered in ClinicalTrials.gov: Cross sectional analysis

Objective To review patterns of publication of clinical trials funded by US National Institutes of Health (NIH) in peer reviewed biomedical journals indexed by Medline. Design Cross sectional analysis. Setting Clinical trials funded by NIH and …

Trial registration 10 years on

This month marks the tenth anniversary of the landmark decision by the International Committee of Medical Journal Editors to make journals require “registration of any clinical trials in a public trials registry at or before the time of first patient …

A future for digital public goods for monitoring SDG indicators

Digital public goods (DPGs), if implemented with effective policies, can facilitate the realization of the United Nations Sustainable Development Goals (SDGs). However, there are ongoing deliberations on how to define DPGs and assure that society can …

Are Preregistration and Registered Reports Vulnerable to Hacking?

Preregistration of study hypotheses has been proclaimed as the “revolution”1 to curb publication bias and data dredging such as p-hacking and HARKing, i.e., hypothesizing after results are known. Many publishers encourage preregistration in their …

Big team science initiatives: A catalyst for trustworthy advancements in IO psychology

Keener et al. (2023) raise concerns about the trustworthiness of Industrial/Organizational (IO) Psychology research and related fields due to the low reproducibility and replicability of research findings. The authors provide various solutions to …

From policy to practice: Lessons learned from an open science funding initiative

In the past few years, there has been a notable shift in the open science landscape as more countries and international agencies release recommendations and implementation guidelines for open scholarship. In August 2022, the US White House Office of …
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