Resources

Nosek et al. (1) recently joined others in advocating for “widespread adoption of preregistration” as a tool for advancing science. The language they use in making this important argument, however, creates unnecessary confusion: Like many others …

A large amount of variation exists in beliefs about the purpose and benefits of preregistration, making it difficult to implement and evaluate, and limiting its usefulness. Additionally, no single resource exists to describe what a preregistration …

Context Recent reports highlight gaps between guidelines-based treatment recommendations and evidence from clinical trials that supports those recommendations. Strengthened reporting requirements for studies registered with ClinicalTrials.gov enable …

Preregistration requires scientists to describe the planned research activities before their project begins. Preregistration improves transparency in empirical research and is an institutional response to scientific misconduct. This paper studies the …

The methods and results of health research are documented in study protocols, full study reports (detailing all analyses), journal reports, and participant-level datasets. However, protocols, full study reports, and participant-level datasets are …

Study preregistration is one of several “open science” practices (e.g., open data, preprints) that researchers use to improve the transparency and rigour of their research. As more researchers adopt preregistration as a regular research practice, …

Objective To review patterns of publication of clinical trials funded by US National Institutes of Health (NIH) in peer reviewed biomedical journals indexed by Medline. Design Cross sectional analysis. Setting Clinical trials funded by NIH and …

This month marks the tenth anniversary of the landmark decision by the International Committee of Medical Journal Editors to make journals require “registration of any clinical trials in a public trials registry at or before the time of first patient …

Digital public goods (DPGs), if implemented with effective policies, can facilitate the realization of the United Nations Sustainable Development Goals (SDGs). However, there are ongoing deliberations on how to define DPGs and assure that society can …

Preregistration of study hypotheses has been proclaimed as the “revolution”1 to curb publication bias and data dredging such as p-hacking and HARKing, i.e., hypothesizing after results are known. Many publishers encourage preregistration in their …