Resources

We argue that many of the crises currently afflicting science can be associated with a present failure of science to sufficiently embody its own values. Here, we propose a response beyond mere crisis resolution based on the observation that an …

A systematic review is a rigorous process that involves identifying, selecting, and synthesizing available evidence pertaining to an a priori–defined research question. The resulting evidence base may be summarized qualitatively or through a …

The 2015 consensus statement published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group and the European Cooperation in Science and Technology ( COST) Action ASL in Dementia aimed to encourage the …

Altruism and trust lie at the heart of research on human subjects. Altruistic individuals volunteer for research because they trust that their participation will contribute to improved health for others and that researchers will minimise risks to …

In 2005, the International Committee of Medical Journal Editors (ICMJE) initiated a policy requiring investigators to deposit information about trial design into an accepted clinical trials registry before the onset of patient enrolment. 1 This …

All parties associated in clinical trials—patients, doctors, scientists, industry—share a common desire for a vigorous clinical research enterprise that brings innovations to patients as quickly as possible. However, recent scandals in the UK and …

Preregistration is the practice of publicly publishing plans on central components of the research process before access to, or collection, of data. Within the context of the replication crisis, open science practices like preregistration have been …

Social science research has undergone a credibility revolution, but these gains are at risk due to problematic research practices. Existing research on transparency has centered around randomized controlled trials, which constitute only a small …

Pre-Analysis Plans (PAPs) for randomized evaluations are becoming increasingly common in Economics, but their definition remains unclear and their practical applications therefore vary widely. Based on our collective experiences as researchers and …

Objective: To describe the frequency of open science practices in a contemporary sample of studies developing prognostic models using machine-learning methods in the field of oncology. Study design and setting: We conducted a systematic review, …