eLife

Findings first published in eLife, paired with the replication and reproduction attempts on record. 22 studies in the atlas.

• Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology Errington et al., 2021 — no replication on record
• Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs Wang et al., 2020 — no replication on record
• Saccade suppression depends on context Zimmermann, 2020 — 1 successful
• Lack of evidence for associative learning in pea plants Markel, 2020 — no replication on record
• Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology Kerwin et al., 2020 — no replication on record
• Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis Sheen et al., 2019 — no replication on record
• Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment Essex et al., 2019 — no replication on record
• Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44 Yan et al., 2019 — no replication on record
• Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota Eaton et al., 2018 — no replication on record
• Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc Lewis et al., 2018 — no replication on record
• Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells Vanden Heuvel et al., 2018 — no replication on record
• Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET Kim et al., 2018 — no replication on record
• Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma Repass et al., 2018 — no replication on record
• Large-scale replication study reveals a limit on probabilistic prediction in language comprehension Nieuwland et al., 2018 — no replication on record
• Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia Shan et al., 2017 — no replication on record
• Replication Study: BET bromodomain inhibition as a therapeutic strategy to target c-Myc Aird et al., 2017 — no replication on record
• Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data Kandela & Aird, 2017 — no replication on record
• Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations Horrigan et al., 2017 — no replication on record
• Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs Mantis et al., 2017 — no replication on record
• Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting… Showalter et al., 2017 — no replication on record
• Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors Horrigan, 2017 — no replication on record
• Registered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma Repass et al., 2016 — 1 failed