Background: We explore whether the number of null results in large National Heart Lung, and Blood Institute (NHLBI) funded trials has increased over time. Methods: We identified all large NHLBI supported RCTs between 1970 and 2012 evaluating drugs or …
A combination of confirmation bias, hindsight bias, and pressure to publish may prompt the (unconscious) exploration of various methodological options and reporting only the ones that lead to a (statistically) significant outcome. This undisclosed …
The results of many published studies across many scientific domains are not easily reproduced by independent laboratories. For example, an initiative by Bayer Healthcare to replicate 67 pre-clinical studies led to a reproducibility rate of 20-25% …
This mini course was designed to introduce Psychology undergraduate students at the University of Edinburgh (who are working on their dissertation in the academic year 2021-2022) to open research principles and practices.
The course contains 5 …
Like performance-enhancing drugs inflating apparent athletic achievements, several common social science practices contribute to the production of illusory results. In this article, we examine the processes that lead to illusory findings and describe …
In this commentary on Simmons, Nelson, and Simonsohn (this issue), we examine their rationale for pre-registration within the broader perspective of what good science is. We agree that there is potential benefit in a system of pre-registration if …
In his commentary, Klonsky (2024) outlines several arguments for why preregistration mandates (PRMs) will have a negative impact on the field. Klonsky’s overarching concern is that when preregistration ceases to be a tool for research and becomes an …
This course will examine current controversies and new developments in research methods in psychology. The goal of the course is to learn to think critically about how psychological science is conducted and how conclusions are drawn. We will cover …
Psychological research is in the midst of what has been called the “replication crisis”, in which questions have been raised about the validity of even seminal research findings. How can we tell if the research we’re reading and doing is rigorous and …