Preregistration

Preregistration of animal research protocols: development and 3-year overview of preclinicaltrials.eu

Open, prospective registration of a study protocol can improve research rigour in a number of ways. Through preregistration, key features of the study’s methodology are recorded and maintained as a permanent record, enabling comparison of the …

Preregistration of Epidemiologic Studies: An Ill-founded Mix of Ideas

The idea for the registration of observational epidemiologic studies (with their protocols, hypotheses, and analysis plans) is modeled on the registration of randomized clinical trials (RCTs). The movement that led to the registration of RCTs was fed …

Preregistration of Epidemiology Protocols (Author Response)

Professors Kogevinas and Stayner do not address the central point of my commentary but they do pursue an issue on which I welcome the opportunity to elucidate. As a student of epidemiology myself, I appreciate professors who are more critical of …

Preregistration of Epidemiology Protocols (Response)

There must be something wrong when a professor of epidemiology includes the following statement in the concluding remarks of a commentary he has written: “Whether observational epidemiology has, on balance, contributed more to the good of public …

Preregistration of Epidemiology Protocols: A Commentary in Support

It has been proposed that observational epidemiology protocols, just like those for randomized controlled trials (RCTs), should be preregistered. Unlike the editors of the Lancet and BMJ who have endorsed the proposal, the Epidemiology editors and 5 …

Preregistration of exploratory research: Learning from the golden age of discovery

Preregistration of study protocols and, in particular, Registered Reports are novel publishing formats that are currently gaining substantial traction. Besides rating the research question and soundness of methodology over outstanding significance of …

Preregistration of Information Systems Research

In this paper, we introduce the preregistration concept for experiments in the information systems (IS) discipline. Preregistration constitutes a way to commit to analytic steps before collecting or observing data and, thus, mitigate any biases …

Preregistration of Machine Learning Research

It is interesting to note that human intelligence thrives on what Peirce called abductive inferences (Peirce and Turrisi 1997, 241-56), which are neither inductive nor deductive. Abductive inferencing basically entails an informed guess as to the …

Preregistration of Modeling Exercises May Not Be Useful

This is a commentary on Lee et al.’s (2019) article encouraging preregistration of model development, fitting, and evaluation. While we are in general agreement with Lee et al.’s characterization of the modeling process, we disagree on whether …

Preregistration of Randomized Controlled Trials

Randomized controlled trials (RCTs) are designed to answer causal questions with internal validity. However, threats to internal validity exist for even well-designed RCTs. In this article, we focus on how preregistration can help address some …