Preregistration

Catalyzing communities of research rigour champions

The biomedical sciences must maintain and enhance a research culture that prioritizes rigour and transparency. The US National Institute of Neurological Disorders and Stroke convened a workshop entitled ‘Catalyzing Communities of Research Rigor …

Challenges and opportunities in preregistration of coordinated data analysis: A tutorial and template

The credibility revolution in social science has led to the recommendation and adoption of practices to increase the replicability of scientific findings. Many of the recommended practices, such as replication and preregistration, present unique …

Characteristics of Clinical Trials Registered in ClinicalTrials.gov, 2007-2010

Context Recent reports highlight gaps between guidelines-based treatment recommendations and evidence from clinical trials that supports those recommendations. Strengthened reporting requirements for studies registered with ClinicalTrials.gov enable …

Ciência aberta e reprodutível

Esta disciplina destina-se a alunos em níveis de Mestrado e Doutorado do Programade Pós-Graduação em Ciências da Saúde: Cardiologia e Ciências Cardiovasculares e outros programas de pós-graduação. A disciplina está estruturada para promover discussão …

Circle of Willis (episode with Simine Vazire)

Welcome to Episode 8, where I talk to SIMINE VAZIRE, Associate Professor of Psychology at the University of California at Davis, about the stability of personality, our ability to know ourselves, and some of the nuances within the prescriptive advice …

CJEP will offer open science badges

This editorial announces the decision of the Canadian Journal of Experimental Psychology (CJEP) to offer Open Science Framework (OSF) Badges. The Centre for Open Science provides tools to facilitate open science practices. These include the OSF …

Claims about scientific rigour require rigour

Protzko et al.1 describe a project in which internal tests of pilot-tested hypotheses and independent replications embraced “rigour-enhancing practices” such as confirmatory tests, large sample sizes, preregistration and methodological transparency. …

Clinical trial registration: A statement from the International Committee of Medical Journal Editors

Altruism and trust lie at the heart of research on human subjects. Altruistic individuals volunteer for research because they trust that their participation will contribute to improved health for others and that researchers will minimise risks to …

Clinical trial registration: Looking back and moving ahead

In 2005, the International Committee of Medical Journal Editors (ICMJE) initiated a policy requiring investigators to deposit information about trial design into an accepted clinical trials registry before the onset of patient enrolment. 1 This …

Clinical trial registration: transparency is the watchword

All parties associated in clinical trials—patients, doctors, scientists, industry—share a common desire for a vigorous clinical research enterprise that brings innovations to patients as quickly as possible. However, recent scandals in the UK and …