Context Recent reports highlight gaps between guidelines-based treatment recommendations and evidence from clinical trials that supports those recommendations. Strengthened reporting requirements for studies registered with ClinicalTrials.gov enable …
Esta disciplina destina-se a alunos em nÃveis de Mestrado e Doutorado do Programade Pós-Graduação em Ciências da Saúde: Cardiologia e Ciências Cardiovasculares e outros programas de pós-graduação. A disciplina está estruturada para promover discussão …
Welcome to Episode 8, where I talk to SIMINE VAZIRE, Associate Professor of Psychology at the University of California at Davis, about the stability of personality, our ability to know ourselves, and some of the nuances within the prescriptive advice …
Altruism and trust lie at the heart of research on human subjects. Altruistic individuals volunteer for research because they trust that their participation will contribute to improved health for others and that researchers will minimise risks to …
In 2005, the International Committee of Medical Journal Editors (ICMJE) initiated a policy requiring investigators to deposit information about trial design into an accepted clinical trials registry before the onset of patient enrolment. 1 This …
All parties associated in clinical trials—patients, doctors, scientists, industry—share a common desire for a vigorous clinical research enterprise that brings innovations to patients as quickly as possible. However, recent scandals in the UK and …
In psychology, preregistration is the most widely used method to ensure the confirmatory status of analyses. However, the method has disadvantages: Not only is it perceived as effortful and time-consuming, but reasonable deviations from the analysis …
Preregistration forces researchers to front-load a lot of decision-making to an early stage of a project. Choosing which preregistration platform to use is one of those early decisions, and because a preregistration cannot be moved, that choice is …
Context: As of 2005, the International Committee of Medical Journal Editors required investigators to register their trials prior to participant enrollment as a precondition for publishing the trial's findings in member journals. Objective: To assess …