Preregistration

Clinical trial registration: Looking back and moving ahead

In 2005, the International Committee of Medical Journal Editors (ICMJE) initiated a policy requiring investigators to deposit information about trial design into an accepted clinical trials registry before the onset of patient enrolment. 1 This …

Clinical trial registration: transparency is the watchword

All parties associated in clinical trials—patients, doctors, scientists, industry—share a common desire for a vigorous clinical research enterprise that brings innovations to patients as quickly as possible. However, recent scandals in the UK and …

Cognitive Science StackExchange site (for psychology Q&A)

A website about questions on psychology

Comparing Analysis Blinding With Preregistration in the Many-Analysts Religion Project

In psychology, preregistration is the most widely used method to ensure the confirmatory status of analyses. However, the method has disadvantages: Not only is it perceived as effortful and time-consuming, but reasonable deviations from the analysis …

Comparison of Preregistration Platforms

Preregistration forces researchers to front-load a lot of decision-making to an early stage of a project. Choosing which preregistration platform to use is one of those early decisions, and because a preregistration cannot be moved, that choice is …

Comparison of Registered and Published Primary Outcomes in Randomized Controlled Trials

Context: As of 2005, the International Committee of Medical Journal Editors required investigators to register their trials prior to participant enrollment as a precondition for publishing the trial's findings in member journals. Objective: To assess …

CrossValidated StackExchange site (for statistics Q&A)

A website about questions on statistics

Curtailing the Use of Preregistration: A Misused Term

Improving the usability of psychological research has been encouraged through practices such as prospectively registering research plans. Registering research aligns with the open-science movement, as the registration of research protocols in …

Declaration of common standards for the preregistration of animal research—speeding up the scientific progress

Preregistration of studies is a recognized tool in clinical research to improve the quality and reporting of all gained results. In preclinical research, preregistration could boost the translation of published results into clinical breakthroughs. …

Designing for Preregistration: A User-Centered Perspective

The replication crisis---a failure to replicate foundational studies---has sparked a conversation in psychology, HCI, and beyond about scientific reliability. To address the crisis, researchers increasingly adopt preregistration: the practice of …