Replication Research

 

Campbell’s Law Explains the Replication Crisis: Pre-Registration Badges Are History Repeating

Campbell’s Law explains the replication crisis. In brief, useful tools such as hypotheses, p-values, and multi-study designs came to be viewed as indicators of strong science, and thus goals in and of themselves. Consequently, their use became …

Exploring regulatory flexibility to create novel incentives to optimize drug discovery

Efforts by governments, firms, and patients to deliver pioneering drugs for critical health needs face a challenge of diminishing efficiency in developing those medicines. While multi-sectoral collaborations involving firms, researchers, patients, …

Biden-⁠Harris Administration Marks the Anniversary of OSTP’s Year of Open Science

One year ago, the White House Office of Science and Technology Policy (OSTP) launched a Year of Open Science, announcing actions across the federal government to advance open, equitable, and secure research. Throughout 2023, federal agencies engaged …

Harvard Teaching Hospital Seeks Retraction of Six Papers by Top Researchers

The Dana-Farber Cancer Institute, a Harvard Medical School affiliate, is seeking to retract six studies and correct 31 other papers as part of a probe involving four of its senior cancer researchers and administrators.

The reporting completeness and transparency of systematic reviews of prognostic prediction models for COVID-19 was poor: a methodological overview of systematic reviews

Objectives To conduct a methodological overview of reviews to evaluate the reporting completeness and transparency of systematic reviews (SRs) of prognostic prediction models (PPMs) for COVID-19. Study Design and Setting MEDLINE, Scopus, Cochrane …

A recipe for extremely reproducible enrichment analysis (and why we need it)

Unreliable and irreproducible research is a significant problem that wastes resources and risks undermining the public perception of science. Previous work has highlighted that published enrichment analyses frequently suffer from statistical and …

Optimizing the methodology of human sleep and memory research

Understanding the complex relationship between sleep and memory consolidation is a major challenge in cognitive neuroscience and psychology. Many studies suggest that sleep triggers off-line memory processes, resulting in less forgetting of …

Last Contact: A Science Adventure

Last Contact is a game is a game that is intended to inform people about the open science movement. In the game players encounter common problems of current scientific practice in form of a parody science fiction scenario. The problems that players …

The need for public opinion and survey methodology research to embrace preregistration and replication, exemplified by a team’s failure to replicate their own findings on visual cues in grid-type questions

Survey researchers take great care to measure respondents’ answers in an unbiased way; but, how successful are we as a field at remedying unintended and intended biases in our research? The validity of inferences drawn from studies has been found to …

Adapting open science and pre-registration to longitudinal research

Open science practices, such as pre-registration and data sharing, increase transparency and may improve the replicability of developmental science. However, developmental science has lagged behind other fields in implementing open science practices. …
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