Background
Transcriptomes present a rich, multi-dimensional subset of genomics data. They provide broad insights into genetic sequence, and more significantly gene expression, across biological samples. This technology is frequently employed for …
Research resources like transgenic animals and antibodies are the workhorses of biomedicine, enabling investigators to relatively easily study specific disease conditions. As key biological resources, transgenic animals and antibodies are often …
Objectives
This study evaluates the endorsement of open science practices by dental journals.
Materials and methods
This was a meta-research study that included journals listed in the 2021 Journal Citation Reports under Dentistry. A comprehensive …
Scientific meetings are an important venue for disseminating findings, but space and time for experimental design details is often limited. Thus, to facilitate increased transparency in scientific presentations, rigor icons can quickly and easily …
In 2009, the climate research community was rocked by the Climategate controversy, an email leak that allegedly provided evidence of data manipulation [1]. While that allegation was shown to be unsubstantiated [2], it focused the community’s …
Open science ensures that research is transparently reported and freely accessible for all to assess and collaboratively build on. Psychiatric genetics has led among the health sciences in implementing some open science practices in common study …
Objectives
To conduct a methodological overview of reviews to evaluate the reporting completeness and transparency of systematic reviews (SRs) of prognostic prediction models (PPMs) for COVID-19.
Study Design and Setting
MEDLINE, Scopus, Cochrane …
Protecting privacy and ensuring confidentiality in data is a critical component of modernizing our national data infrastructure. The use of blended data - combining previously collected data sources - presents new considerations for responsible data …
Statisticians have been keen to critique statistical aspects of the “replication crisis” in other scientific disciplines. But new statistical tools are often published and promoted without any thought to replicability. This needs to change, argue …
Research is cumulative. New investigations build on, challenge, or qualify claims based on prior evidence. When we have limited evidence, it is normal that some explanations are wrong and need to be refined or reconsidered. This self-corrective …