About this resource

    Type of resources
    Primary Source, Reading, Paper
    Education level(s)
    College / Upper Division (Undergraduates)
    Primary user(s)
    Student
    Subject area(s)
    Applied Science, Life Science, Social Science
    Language(s)
    English
    Cluster
    Pre-analysis Planning
    Last updated
    11 June 2020
    Primary SourceReadingPaper

    Making Prospective Registration of Observational Research a Reality

    By Rafael Dal-Ré, John P. Ioannidis, Michael B. Bracken, Patricia A. Buffler, An-Wen Chan, Eduardo L. Franco, Carlo La Vecchia, ElisabeteWeiderpass

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    Level College / Upper Division (Undergraduates) · For Student · Language English

    Abstract

    The vast majority of health-related observational studies are not prospectively registered and the advantages of registration have not been fully appreciated. Nonetheless, international standards require approval of study protocols by an independent ethics committee before the study can begin. We suggest that there is an ethical and scientific imperative to publicly preregister key information from newly approved protocols, which should be required by funders. Ultimately, more complete information may be publicly available by disclosing protocols, analysis plans, data sets, and raw data.

    Keywords Reproducibility Crisis and Credibility Revolution