Reproducibility Immersive Course

Abstract

Various fields in the natural and social sciences face a ‘crisis of confidence’. Broadly, this crisis amounts to a pervasiveness of non-reproducible results in the published literature. For example, in the field of biomedicine, Amgen published findings that out of 53 landmark published results of pre-clinical studies, only 11% could be replicated successfully. This crisis is not confined to biomedicine. Areas that have recently received attention for non-reproducibility include biomedicine, economics, political science, psychology, as well as philosophy. Some scholars anticipate the expansion of this crisis to other disciplines. This course explores the state of reproducibility. After giving a brief historical perspective, case studies from different disciplines (biomedicine, psychology, and philosophy) are examined to understand the issues concretely. Subsequently, problems that lead to non-reproducibility are discussed as well as possible solutions and paths forward.