About this resource

    Type of resources
    Reading
    Education level(s)
    Graduate / Professional
    Primary user(s)
    student, teacher
    Subject area(s)
    Biology
    Language(s)
    English
    Cluster
    Replication and Meta-Research, Conceptual and Statistical Knowledge
    Last updated
    1 January 2020
    Reading

    Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

    By Aaron Lawson McLean, Aikaterini Kyriakopoulou, Andrew Thomson, Aparna Potluru, Arno de Wilde, Cristina Nunes-Fonseca, David W. Howells, Emily S. Sena, Gillian L. Currie, Hanna Vesterinen, Julija Baginskitae, Kieren Egan, Leonid Churilov, Malcolm R. Macleod, Nicki Sherratt, Rachel Hemblade, Stylianos Serghiou, Theo Hirst, Zsanett Bahor

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    Level Graduate / Professional · For student, teacher · Language English

    Abstract

    The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.

    Keywords Bibliometrics · Experimental Design · Publishing · Research Assessment · Research Quality Assessment · Research Validity · Scientific Publishing · Scientists · Systematic Reviews