Drug Therapy

Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discovery

There is a scarcity of novel treatments to address many unmet medical needs. Industry and academia are finally coming to terms with the fact that the prevalent models and incentives for innovation in early stage drug discovery are failing to promote …

The Economics of Reproducibility in Preclinical Research

Low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development. An analysis of past studies indicates that the cumulative (total) prevalence of …