Genomics

Data Wrangling and Processing for Genomics

Data Carpentry lesson to learn how to use command-line tools to perform quality control, align reads to a reference genome, and identify and visualize between-sample variation. A lot of genomics analysis is done using command-line tools for three …

Development of an open access, virtual bioinformatics lab for students in medical laboratory sciences

Objectives Despite the growing importance of bioinformatics in molecular diagnostics, not all medical laboratory sciences (MLS) programs provide instruction in this field. We developed and assessed a virtual laboratory learning unit to introduce …

Empirical Study of Data Sharing by Authors Publishing in PLoS Journals

Background Many journals now require authors share their data with other investigators, either by depositing the data in a public repository or making it freely available upon request. These policies are explicit, but remain largely untested. We …

Genomics Workshop Overview

Workshop overview for the Data Carpentry genomics curriculum. Data Carpentry’s aim is to teach researchers basic concepts, skills, and tools for working with data so that they can get more done in less time, and with less pain. This workshop teaches …

Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics

Proprietary genetic datasets are valuable for boosting the statistical power of genome-wide association studies (GWASs), but their use can restrict investigators from publicly sharing the resulting summary statistics. Although researchers can resort …

Project Organization and Management for Genomics

Data Carpentry Genomics workshop lesson to learn how to structure your metadata, organize and document your genomics data and bioinformatics workflow, and access data on the NCBI sequence read archive (SRA) database. Good data organization is the …