Metascience

A survey on how preregistration affects the research workflow: better science but more work

The preregistration of research protocols and analysis plans is a main reform innovation to counteract confirmation bias in the social and behavioural sciences. While theoretical reasons to preregister are frequently discussed in the literature, the …

Association between trial registration and treatment effect estimates: a meta-epidemiological study

To increase transparency in research, the International Committee of Medical Journal Editors required, in 2005, prospective registration of clinical trials as a condition to publication. However, many trials remain unregistered or retrospectively …

Comparing Analysis Blinding With Preregistration in the Many-Analysts Religion Project

In psychology, preregistration is the most widely used method to ensure the confirmatory status of analyses. However, the method has disadvantages: Not only is it perceived as effortful and time-consuming, but reasonable deviations from the analysis …

Computational social science is growing up: why puberty consists of embracing measurement validation, theory development, and open science practices

Puberty is a phase in which individuals often test the boundaries of themselves and surrounding others and further define their identity – and thus their uniqueness compared to other individuals. Similarly, as Computational Social Science (CSS) grows …

CONSORT statement adherence and risk of bias in randomized controlled trials on deep caries management: a meta-research

Background Recently, trials have supported changes in deep caries management. However, reporting might lack details, affecting interpretation and implementation. Thus, we aimed to evaluate the adherence to the CONSORT statement and the risk of bias …

Meta-assessment of bias in science

Numerous biases are believed to affect the scientific literature, but their actual prevalence across disciplines is unknown. To gain a comprehensive picture of the potential imprint of bias in science, we probed for the most commonly postulated …

Reflections on the Unintended Consequences of the Science Reform Movement

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Reproducibility in Cancer Biology: The challenges of replication

Interpreting the first results from the Reproducibility Project: Cancer Biology requires a highly nuanced approach. Reproducibility is a cornerstone of science, and the development of new drugs and medical treatments relies on the results of …

Science isn't Broken

If you follow the headlines, your confidence in science may have taken a hit lately. Peer review? More like self-review. An investigation in November uncovered a scam in which researchers were rubber-stamping their own work, circumventing peer review …

Sorry we′re open, come in we're closed: different profiles in the perceived applicability of open science practices to completed research projects

Open science is an increasingly important topic for research, politics and funding agencies. However, the discourse on open science is heavily influenced by certain research fields and paradigms, leading to the risk of generalizing what counts as …