Metascience

 

Science isn't Broken

If you follow the headlines, your confidence in science may have taken a hit lately. Peer review? More like self-review. An investigation in November uncovered a scam in which researchers were rubber-stamping their own work, circumventing peer review …

The replication crisis is less of a “crisis” in the Lakatosian approach than it is in the Popperian and naïve methodological falsificationism approaches

Popper’s (1983, 2002) philosophy of science has enjoyed something of a renaissance in the wake of the replication crisis, offering a philosophical basis for the ensuing science reform movement. However, adherence to Popper’s approach may also be at …

Association between trial registration and treatment effect estimates: a meta-epidemiological study

To increase transparency in research, the International Committee of Medical Journal Editors required, in 2005, prospective registration of clinical trials as a condition to publication. However, many trials remain unregistered or retrospectively …

Meta-assessment of bias in science

Numerous biases are believed to affect the scientific literature, but their actual prevalence across disciplines is unknown. To gain a comprehensive picture of the potential imprint of bias in science, we probed for the most commonly postulated …

Reproducibility in Cancer Biology: The challenges of replication

Interpreting the first results from the Reproducibility Project: Cancer Biology requires a highly nuanced approach. Reproducibility is a cornerstone of science, and the development of new drugs and medical treatments relies on the results of …

What is this thing called open science?

A general introduction to open scholarship.
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