Phase I Clinical Investigation

Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discovery

There is a scarcity of novel treatments to address many unmet medical needs. Industry and academia are finally coming to terms with the fact that the prevalent models and incentives for innovation in early stage drug discovery are failing to promote …

Trial Publication after Registration in ClinicalTrials.Gov: A Cross-Sectional Analysis

Background ClinicalTrials.gov is a publicly accessible, Internet-based registry of clinical trials managed by the US National Library of Medicine that has the potential to address selective trial publication. Our objectives were to examine …