Objective To review patterns of publication of clinical trials funded by US National Institutes of Health (NIH) in peer reviewed biomedical journals indexed by Medline. Design Cross sectional analysis. Setting Clinical trials funded by NIH and …
Objectives
The ultimate goal of biomedical research is the development of new treatment options for patients. Animal models are used if questions cannot be addressed otherwise. Currently, it is widely believed that a large fraction of performed …
Secondary data analyses occur when new analyses are proposed for existing data. Although they are prevalent in special education research, there is little guidance on how to prepare secondary data analyses studies. Preregistration of secondary data …
Discussions of how to improve research quality are predominant in a number of fields, including education. But how prevalent are the use of problematic practices and the improved practices meant to counter them? This baseline information will be a …
The credibility of psychological findings can be undermined by a history of questionable research practices (QRPs) by researchers. One remedy for this problem is the pre-registration of a study in which a research protocol is registered before …
Flexibility in the design, analysis and interpretation of scientific studies creates a multiplicity of possible research outcomes. Scientists are granted considerable latitude to selectively use and report the hypotheses, variables and analyses that …
Ledgerwood (1) argues that there are two independent uses of preregistration that are conflated in Nosek et al. (2) and elsewhere: “Preregistering theoretical predictions enables theory falsifiability. Preregistering analysis plans enables type I …
The preregistration of research plans and hypotheses may prevent publication bias and questionable research practices. We incorporated a modified version of the preregistration process into an undergraduate capstone research course. Students …
This article describes the current debate on the practice of preregistration in political science—that is, publicly releasing a research design before observing outcome data. The case in favor of preregistration maintains that it can restrain four …
There is an ongoing debate regarding preregistration of epidemiologic study protocols. We examine the basic idea that preregistration of study protocols and their associated hypotheses would enhance the reliability of observational research. We …