Registration

Association between trial registration and treatment effect estimates: a meta-epidemiological study

To increase transparency in research, the International Committee of Medical Journal Editors required, in 2005, prospective registration of clinical trials as a condition to publication. However, many trials remain unregistered or retrospectively …

COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time

Discrepancies between pre-specified and reported outcomes are an important source of bias in trials. Despite legislation, guidelines and public commitments on correct reporting from journals, outcome misreporting continues to be prevalent. We aimed …

Curtailing the Use of Preregistration: A Misused Term

Improving the usability of psychological research has been encouraged through practices such as prospectively registering research plans. Registering research aligns with the open-science movement, as the registration of research protocols in …

Discrepancies in the Registries of Diet vs Drug Trials

This cross-sectional study examines discrepancies between registered protocols and subsequent publications for drug and diet trials whose findings were published in prominent clinical journals in the last decade. ClinicalTrials.gov was established in …

Increasing the transparency of systematic reviews: Presenting a generalized registration form

This paper presents a generalized registration form for systematic reviews that can be used when currently available forms are not adequate. The form is designed to be applicable across disciplines (i.e., psychology, economics, law, physics, or any …

Supporting study registration to reduce research waste

An estimated 82–89% of ecological research and 85% of medical research has limited or no value to the end user because of various inefficiencies. We argue that registration and registered reports can enhance the quality and impact of ecological …