Reproducibility

 

Research Integrity definitions and challenges

Research integrity is guided by a set of principles to ensure research reliability and rigor. It serves as a pillar to uphold society’s trust in science and foster scientific progress. However, over the past 2 decades, a surge in research integrity …

GelBox: Open-source software to improve rigor and reproducibility when analyzing gels and immunoblots

GelBox is open-source software that was developed with the goal of enhancing rigor, reproducibility, and transparency when analyzing gels and immunoblots. It combines image adjustments (cropping, rotation, brightness, and contrast), background …

Adapting open science and pre-registration to longitudinal research

Open science practices, such as pre-registration and data sharing, increase transparency and may improve the replicability of developmental science. However, developmental science has lagged behind other fields in implementing open science practices. …

Decatastrophizing research irreproducibility

The reported inability to replicate research findings from the published literature precipitated extensive efforts to identify and correct perceived deficiencies in the execution and reporting of biomedical research. Despite these efforts, …

Advocating for Generalizability: Accepting Inherent Variability in Translation of Animal Research Outcomes

Advancing scientific discovery requires investigators to embrace research practices that increase transparency and disclosure about materials, methods, and outcomes. Several research advocacy and funding organizations have produced guidelines and …

Building transparency and reproducibility into the practice of pharmacoepidemiology and outcomes research

Real-world evidence (RWE) studies are increasingly used to inform policy and clinical decisions. However, there remain concerns about the credibility and reproducibility of RWE studies. While there is universal agreement on the critical importance of …

Catalyzing communities of research rigour champions

The biomedical sciences must maintain and enhance a research culture that prioritizes rigour and transparency. The US National Institute of Neurological Disorders and Stroke convened a workshop entitled ‘Catalyzing Communities of Research Rigor …

Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact

Research resources like transgenic animals and antibodies are the workhorses of biomedicine, enabling investigators to relatively easily study specific disease conditions. As key biological resources, transgenic animals and antibodies are often …

Open Science Practices in Psychiatric Genetics: A Primer

Open science ensures that research is transparently reported and freely accessible for all to assess and collaboratively build on. Psychiatric genetics has led among the health sciences in implementing some open science practices in common study …

Opening open science to all: Demystifying reproducibility and transparency practices in linguistic research

In recent years, numerous fields of research have seen a push for increased reproducibility and transparency practices. As a result, specific transparency practices have emerged, such as open access publishing, preregistration, sharing data, …
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