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G protein β3 subunit 825 TT genotype and post-pregnancy weight retention

Achim Gutersohn, Christoph Naber, Norbert Müller, Raimund Erbel, Winfried Siffert

The Lancet, 2000. DOI 10.1016/s0140-6736(00)02093-6

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed. The earliest on record is from 2009.

Replications

• Genetic Variation in Female BMI Increases with Number of Children Born but Failure to Replicate Association betweenGNβ3Variants and Increased BMI in Parous Females, Cornes et al. (2009). Twin Research and Human Genetics. Outcome recorded: failed. Hence, we attempted to replicate this association and test an additional three SNPs also located near or on GNβ3 (rs10744716 (upstream), rs5442 (exon 10), rs5446 (exon 11)) in a sample of 3131 females and 1693 males from 2585 twin families. No association was found between these SNPs among females, even when allowing for a genotype by parity effect. Read from abstract. View paper

Cite this record

Gutersohn, A., Naber, C., Müller, N., Erbel, R., & Siffert, W. (2000). G protein β3 subunit 825 TT genotype and post-pregnancy weight retention. The Lancet, 355(9211), 1240–1241. https://doi.org/10.1016/s0140-6736(00)02093-6

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