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A Genome Scan for Modifiers of Age at Onset in Huntington Disease: The HD MAPS Study

Jian-Liang Li, Michael R. Hayden, Elisabeth W. Almqvist, Ryan R. Brinkman, Alexandra Durr, Catherine Dodé, Patrick J. Morrison, Oksana Suchowersky, Christopher A. Ross, Russell L. Margolis, Adam Rosenblatt, Estrella Gómez-Tortosa, David Mayo Cabrero, Andrea Novelletto, Marina Frontali, Martha Nance, Ronald J.A. Trent, Elizabeth McCusker, Randi Jones, Jane S. Paulsen, Madeline Harrison, Andrea Zanko, Ruth K. Abramson, Ana L. Russ, Beth Knowlton, Luc Djoussé, Jayalakshmi S. Mysore, Suzanne Tariot, Michael F. Gusella, Vanessa C. Wheeler, Larry D. Atwood, L. Adrienne Cupples, Marie Saint-Hilaire, Jang-Ho J. Cha, Steven M. Hersch, Walter J. Koroshetz, James F. Gusella, Marcy E. MacDonald, Richard H. Myers

The American Journal of Human Genetics, 2003. DOI 10.1086/378133

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful.

Replications

• Genome-wide significance for a modifier of age at neurological onset in Huntington's Disease at 6q23-24: the HD MAPS study, Li et al. (2006). Outcome recorded: successful. In this replication study, linkage for modifier of age at onset in HD was confirmed at 6q23-24. View paper

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