Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p

Helen M. Broadbent, John F. Peden, Stefan Lorkowski, Anuj Goel, Halit Ongen, Fiona Green, Robert Clarke, Rory Collins, Maria Grazia Franzosi, Gianni Tognoni, Udo Seedorf, Stephan Rust, Per Eriksson, Anders Hamsten, Martin Farrall, Hugh Watkins

Human Molecular Genetics, 2007. DOI 10.1093/hmg/ddm352

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2010.

Replications

Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population, Gori et al. (2010). BMC Medical Genetics. Outcome recorded: successful. Our replication study showed that rs2891168 and rs10811661 are independently associated respectively with MI and T2D in an Italian population. Outcome read from the abstract. View paper

Cite this record

Broadbent, H. M., Peden, J. F., Lorkowski, S., Goel, A., Ongen, H., Green, F., Clarke, R., Collins, R., Franzosi, M. G., Tognoni, G., Seedorf, U., Rust, S., Eriksson, P., Hamsten, A., Farrall, M., & Watkins, H. (2007). Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Human Molecular Genetics, 17(6), 806–814. https://doi.org/10.1093/hmg/ddm352

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