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Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p

Helen M. Broadbent, John F. Peden, Stefan Lorkowski, Anuj Goel, Halit Ongen, Fiona Green, Robert Clarke, Rory Collins, Maria Grazia Franzosi, Gianni Tognoni, Udo Seedorf, Stephan Rust, Per Eriksson, Anders Hamsten, Martin Farrall, Hugh Watkins

Human Molecular Genetics, 2007. DOI 10.1093/hmg/ddm352

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful.

Replications

• Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population, Gori et al. (2010). Outcome recorded: successful. Our replication study showed that rs2891168 and rs10811661 are independently associated respectively with MI and T2D in an Italian population. View paper

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