Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

Janelle C. Arthur, Ernesto Perez-Chanona, Marcus Mühlbauer, Sarah Tomkovich, Joshua M. Uronis, Ting-Jia Fan, Barry J. Campbell, Turki Abujamel, Belgin Dogan, Arlin B. Rogers, Jonathan M. Rhodes, Alain Stintzi, Kenneth W. Simpson, Jonathan J. Hansen, Temitope O. Keku, Anthony A. Fodor, Christian Jobin

Science, 2012. DOI 10.1126/science.1224820

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed. The earliest on record is from 2018.

Replications

Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota, Eaton et al. (2018). eLife. Outcome recorded: mixed. We observed no impact on bacterial growth or colonization capacity when the polyketide synthase (pks) genotoxic island was deleted from E. coli NC101, similar to the original study. Outcome read from the abstract. View paper

Cite this record

Arthur, J. C., Perez-Chanona, E., Mühlbauer, M., Tomkovich, S., Uronis, J. M., Fan, T.-J., Campbell, B. J., Abujamel, T., Dogan, B., Rogers, A. B., Rhodes, J. M., Stintzi, A., Simpson, K. W., Hansen, J. J., Keku, T. O., Fodor, A. A., & Jobin, C. (2012). Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota. Science, 338(6103), 120–123. https://doi.org/10.1126/science.1224820

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