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Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing

Xiaojian Shao, Marie Hudson, Ines Colmegna, Celia M. T. Greenwood, Marvin J. Fritzler, Philip Awadalla, Tomi Pastinen, Sasha Bernatsky

Clinical Epigenetics, 2019. DOI 10.1186/s13148-019-0699-9

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed. The earliest on record is from 2021.

Replications

• Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals, Zeng et al. (2021). Genes. Outcome recorded: mixed. we identified 19,472 ACPA-associated differentially methylated cytosines (DMCs), of which 430 overlapped with the 1909 DMCs reported by the original study Outcome read from the abstract. View paper

Cite this record

Shao, X., Hudson, M., Colmegna, I., Greenwood, C. M. T., Fritzler, M. J., Awadalla, P., Pastinen, T., & Bernatsky, S. (2019). Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing. Clinical Epigenetics, 11(1). https://doi.org/10.1186/s13148-019-0699-9

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