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Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

Sudha Seshadri

JAMA, 2010. DOI 10.1001/jama.2010.574

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• Replication of BIN1 Association with Alzheimer's Disease and Evaluation of Genetic Interactions, Carrasquillo et al. (2011). Outcome recorded: mixed. In summary, we provide additional evidence for the variant near BIN1 (rs744373) as a LOAD risk modifier, but our results indicate that the effect of EXOC3L2 independent of APOE ε4 should be studied further. View paper

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