Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia
Has this study been replicated?
The atlas records 1 replication of this study. Recorded outcomes: 1 failed. The earliest on record is from 1993.
Replications
- No association or linkage between polymorphisms at the porphobilinogen deaminase gene locus and schizophrenia, Nöthen et al. (1993). Psychiatric Genetics. Outcome recorded: failed.
Our data from both the association and the linkage study do not support a widespread or consistent involvement of the PBGD gene in the etiology of schizophrenia.
Outcome read from the abstract. View paper
Cite this record
Sanders, A. R., Rincon-Limas, D. E., Chakraborty, R., Grandchamp, B., Hamilton, J. D., Fann, W. E., & Patel, P. I. (1993). Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia. Schizophrenia Research, 8(3), 211–221. https://doi.org/10.1016/0920-9964(93)90019-f
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