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Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain

N. Andrews, E. Legg, D. Lisak, Y. Issop, D. Richardson, S. Harper, T. Pheby, W. Huang, G. Burgess, I. Machin, A.S.C. Rice

European Journal of Pain, 2012. DOI 10.1016/j.ejpain.2011.07.012

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study, Wodarski et al. (2016). Outcome recorded: mixed. Burrowing was significantly suppressed in the majority of studies 24 hours (7 studies/population) and 48 hours (7 TP, 6 SP) after CFA injections. View paper

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