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CNS- and ANS-arousal predict response to antidepressant medication: Findings from the randomized iSPOT-D study

Sebastian Olbrich, Anja Tränkner, Galina Surova, Richard Gevirtz, Evian Gordon, Ulrich Hegerl, Martijn Arns

Journal of Psychiatric Research, 2016. DOI 10.1016/j.jpsychires.2015.12.001

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• NeuroPharm study: EEG wakefulness regulation as a biomarker in MDD, Ip et al. (2021). Outcome recorded: mixed. Responders defined by the iSPOT-D criteria showed a higher propensity toward low vigilance stages in comparison to patients with no response at pretreatment, however, this did not apply when using the NeuroPharm criteria. View paper

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