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Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease

Jason L. Stein, Xue Hua, Jonathan H. Morra, Suh Lee, Derrek P. Hibar, April J. Ho, Alex D. Leow, Arthur W. Toga, Jae Hoon Sul, Hyun Min Kang, Eleazar Eskin, Andrew J. Saykin, Li Shen, Tatiana Foroud, Nathan Pankratz, Matthew J. Huentelman, David W. Craig, Jill D. Gerber, April N. Allen, Jason J. Corneveaux, Dietrich A. Stephan, Jennifer Webster, Bryan M. DeChairo, Steven G. Potkin, Clifford R. Jack, Michael W. Weiner, Paul M. Thompson

NeuroImage, 2010. DOI 10.1016/j.neuroimage.2010.02.068

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• Discovery and replication of gene influences on brain structure using LASSO regression, Kohannim (2012). Outcome recorded: mixed. We were able to successfully replicate the effect of the MACROD2 gene in an independent cohort of 564 young, Australian healthy adult twins and siblings scanned with MRI. View paper

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• Discovery and replication of gene influences on brain structure using LASSO regression
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Failed replications · Successful replications · All browse pages