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A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

Stephan Buch, Clemens Schafmayer, Henry Völzke, Christian Becker, Andre Franke, Huberta von Eller-Eberstein, Christian Kluck, Ingelore Bässmann, Mario Brosch, Frank Lammert, Juan Francisco Miquel, Flavio Nervi, Michael Wittig, Dieter Rosskopf, Birgit Timm, Christine Höll, Marcus Seeger, Abdou ElSharawy, Tim Lu, Jan Egberts, Fred Fändrich, Ulrich R Fölsch, Michael Krawczak, Stefan Schreiber, Peter Nürnberg, Jürgen Tepel, Jochen Hampe

Nature Genetics, 2007. DOI 10.1038/ng2101

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• Identification and Replication of Six Loci Associated With Gallstone Disease, Gellert‐Kristensen et al. (2019). Outcome recorded: mixed. We identified 19 loci to be associated with gallstone disease in the GBE. Of these, 12 were replicated in the Copenhagen cohorts, including six previously unknown loci.... We identified six susceptibility loci for gallstone disease. View paper

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