Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
Has this study been replicated?
The atlas records 1 replication of this study. Recorded outcomes: 1 mixed. The earliest on record is from 2003.
Replications
- Evidence for Genetic Linkage Between a Polymorphism in the Adenosine 2A Receptor and Panic Disorder, Hamilton et al. (2003). Neuropsychopharmacology. Outcome recorded: mixed.
Our findings provide evidence for a susceptibility locus for panic disorder, and possibly including agoraphobia, either within the ADORA2A gene or in a nearby region of chromosome 22, and serves as the first successful candidate gene replication study in panic disorder.
Outcome read from the abstract. View paper
Cite this record
Deckert, J., Nöthen, M. M., Franke, P., Delmo, C., Fritze, J., Knapp, M., Maier, W., Beckmann, H., & Propping, P. (1998). Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease. Molecular Psychiatry, 3(1), 81–85. https://doi.org/10.1038/sj.mp.4000345
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