Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

Jacob L. McCauley, Rebecca L. Zuvich, Ashley H. Beecham, Philip L. De Jager, Ioanna Konidari, Patrice L. Whitehead, Cristin Aubin, Maria Ban, Susan Pobywajlo, Rebeccah Briskin, Susan Romano, Neelum T. Aggarwal, Laura Piccio, Wendy L. McArdle, David P. Strachan, Denis Evans, Anne H. Cross, Bruce Cree, John D. Rioux, Lisa F. Barcellos, Adrian J. Ivinson, Alastair Compston, David A. Hafler, Stephen L. Hauser, Jorge R. Oksenberg, Stephen J. Sawcer, Margaret A. Pericak-Vance, Jonathan L. Haines

Human Molecular Genetics, 2009. DOI 10.1093/hmg/ddp542

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2010.

Replications

Replication of KIF21B as a susceptibility locus for multiple sclerosis: Table 1, Goris et al. (2010). Journal of Medical Genetics. Outcome recorded: successful. We here replicate the association with multiple sclerosis in a Belgian study population of 791 patients and 1098 controls. Outcome read from the abstract. View paper

Cite this record

McCauley, J. L., Zuvich, R. L., Beecham, A. H., De Jager, P. L., Konidari, I., Whitehead, P. L., Aubin, C., Ban, M., Pobywajlo, S., Briskin, R., Romano, S., Aggarwal, N. T., Piccio, L., McArdle, W. L., Strachan, D. P., Evans, D., Cross, A. H., Cree, B., … Haines, J. L. (2009). Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Human Molecular Genetics, 19(5), 953–962. https://doi.org/10.1093/hmg/ddp542

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