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Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

Kazuki N. Sugahara, Tambet Teesalu, Priya Prakash Karmali, Venkata Ramana Kotamraju, Lilach Agemy, Daniel R. Greenwald, Erkki Ruoslahti

Science, 2010. DOI 10.1126/science.1183057

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed. The earliest on record is from 2017.

Replications

• Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs, Mantis et al. (2017). eLife. Outcome recorded: failed. we found that coadministration with iRGD peptide did not have an impact on permeability of the chemotherapeutic agent doxorubicin (DOX) Outcome read from the abstract. View paper

Cite this record

Sugahara, K. N., Teesalu, T., Karmali, P. P., Kotamraju, V. R., Agemy, L., Greenwald, D. R., & Ruoslahti, E. (2010). Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs. Science, 328(5981), 1031–1035. https://doi.org/10.1126/science.1183057

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