A Common Trinucleotide Repeat Expansion within the Transcription Factor 4 (TCF4, E2-2) Gene Predicts Fuchs Corneal Dystrophy

Eric D. Wieben, Ross A. Aleff, Nirubol Tosakulwong, Malinda L. Butz, W. Edward Highsmith, Albert O. Edwards, Keith H. Baratz

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful.

Transethnic Replication of Association of CTG18.1 Repeat Expansion ofTCF4Gene With Fuchs' Corneal Dystrophy in Chinese Implies Common Causal Variant, Xing et al. (2014). Outcome recorded: successful. Our data suggest that the expanded CTG18.1 allele is the main, if not sole, causal variant at this gene locus in the Chinese population. View paper