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A Common Trinucleotide Repeat Expansion within the Transcription Factor 4 (TCF4, E2-2) Gene Predicts Fuchs Corneal Dystrophy

Eric D. Wieben, Ross A. Aleff, Nirubol Tosakulwong, Malinda L. Butz, W. Edward Highsmith, Albert O. Edwards, Keith H. Baratz

PLoS ONE, 2012. DOI 10.1371/journal.pone.0049083

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2014.

Replications

• Transethnic Replication of Association of CTG18.1 Repeat Expansion ofTCF4Gene With Fuchs' Corneal Dystrophy in Chinese Implies Common Causal Variant, Xing et al. (2014). Investigative Opthalmology & Visual Science. Outcome recorded: successful. Our data suggest that the expanded CTG18.1 allele is the main, if not sole, causal variant at this gene locus in the Chinese population. Outcome read from the abstract. View paper

Cite this record

Wieben, E. D., Aleff, R. A., Tosakulwong, N., Butz, M. L., Highsmith, W. E., Edwards, A. O., & Baratz, K. H. (2012). A Common Trinucleotide Repeat Expansion within the Transcription Factor 4 (TCF4, E2-2) Gene Predicts Fuchs Corneal Dystrophy. PLoS ONE, 7(11), e49083. https://doi.org/10.1371/journal.pone.0049083

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