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The Lonely Mouse – Single Housing Affects Serotonergic Signaling Integrity Measured by 8-OH-DPAT-Induced Hypothermia in Male Mice

Otto Kalliokoski, A. Charlotte Teilmann, Kirsten R. Jacobsen, Klas S. P. Abelson, Jann Hau

PLoS ONE, 2014. DOI 10.1371/journal.pone.0111065

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed.

Replications

• Failure to replicate? Exacerbated 8-OH-DPAT-induced hypothermia could not be established in single housed mice when tested as part of a battery of depression tests, Skriver et al. (2019). Outcome recorded: failed. In the present study, we were unable to replicate our previous findings showing an exacerbated 8-OH-DPAT-inducible hypothermic response in single housed male C57BL/6 mice over their group housed counterparts (Kalliokoski et al. 2014). View paper

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