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Components of the Gut Microbiome That Influence Bone Tissue-Level Strength

Marysol Luna, Jason D Guss, Laura S Vasquez-Bolanos, Macy Castaneda, Manuela Vargas Rojas, Jasmin M Strong, Denise A Alabi, Sophie D Dornevil, Jacob C Nixon, Erik A Taylor, Eve Donnelly, Xueyan Fu, M Kyla Shea, Sarah L Booth, Rodrigo Bicalho, Christopher J Hernandez

Journal of Bone and Mineral Research, 2020. DOI 10.1002/jbmr.4341

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed.

Replications

• Effects of high dose aspartame-based sweetener on the gut microbiota and bone strength in young and aged mice, Cyphert et al. (2024). Outcome recorded: failed. Sweetener did not replicate the modifications to the gut microbiome observed in the initial study and did not result in an increase in bone tissue strength in either sex at either age. View paper

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