FOXO3A genotype is strongly associated with human longevity

Bradley J. Willcox, Timothy A. Donlon, Qimei He, Randi Chen, John S. Grove, Katsuhiko Yano, Kamal H. Masaki, D. Craig Willcox, Beatriz Rodriguez, J. David Curb

Proceedings of the National Academy of Sciences, 2008. DOI 10.1073/pnas.0801030105

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed. The earliest on record is from 2010.

Replications

Replication of an association of variation in the FOXO3A gene with human longevity using both case–control and longitudinal data, Soerensen et al. (2010). Aging Cell. Outcome recorded: mixed. Hence, our results support and extent the proposed role of FOXO3A as a candidate longevity gene for survival from younger ages to old age, yet not during old age. Outcome read from the abstract. View paper

Cite this record

Willcox, B. J., Donlon, T. A., He, Q., Chen, R., Grove, J. S., Yano, K., Masaki, K. H., Willcox, D. C., Rodriguez, B., & Curb, J. D. (2008). FOXO3A genotype is strongly associated with human longevity. Proceedings of the National Academy of Sciences, 105(37), 13987–13992. https://doi.org/10.1073/pnas.0801030105

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