Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
Has this study been replicated?
The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2015.
Replications
- Gene-Environment Interaction in Youth Depression: Replication of the 5-HTTLPR Moderation in a Diverse Setting, Rocha et al. (2015). American Journal of Psychiatry. Outcome recorded: successful.
the results corroborated the existence of a measured G×E, now in a large sample from a different sociocultural context.
Outcome read from the abstract. View paper
Cite this record
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., & Poulton, R. (2003). Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene. Science, 301(5631), 386–389. https://doi.org/10.1126/science.1083968
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