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Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

D Franchimont, S Vermeire, H El Housni, M Pierik, K Van Steen, T Gustot, E Quertinmont, M Abramowicz, A Van Gossum, J Devière, P Rutgeerts

Gut, 2004. DOI 10.1136/gut.2003.030205

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed.

Replications

• The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases, De Jager et al. (2007). Outcome recorded: mixed. and Crohn's disease (OR: 1.33, 95% CI: 1.16–1.54; P=0.000035) but not ulcerative colitis. View paper

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