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Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

D Franchimont, S Vermeire, H El Housni, M Pierik, K Van Steen, T Gustot, E Quertinmont, M Abramowicz, A Van Gossum, J Devière, P Rutgeerts

Gut, 2004. DOI 10.1136/gut.2003.030205

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 mixed. The earliest on record is from 2007.

Replications

• The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases, De Jager et al. (2007). Genes & Immunity. Outcome recorded: mixed. and Crohn's disease (OR: 1.33, 95% CI: 1.16–1.54; P=0.000035) but not ulcerative colitis. Outcome read from the abstract. View paper

Cite this record

Franchimont, D., Vermeire, S., El Housni, H., Pierik, M., Van Steen, K., Gustot, T., Quertinmont, E., Abramowicz, M., Van Gossum, A., Devière, J., & Rutgeerts, P. (2004). Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut, 53(7), 987–992. https://doi.org/10.1136/gut.2003.030205

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