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Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Maria Thadani-Mulero, Luigi Portella, Shihua Sun, Matthew Sung, Alexandre Matov, Robert L. Vessella, Eva Corey, David M. Nanus, Stephen R. Plymate, Paraskevi Giannakakou

Cancer Research, 2014. DOI 10.1158/0008-5472.can-13-2876

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed. The earliest on record is from 2018.

Replications

• Replication study: androgen receptor splice variants determine taxane sensitivity in prostate cancer, Shan et al. (2018). PeerJ. Outcome recorded: failed. This result is different from the original study, which reported significant reduction of tumor growth in the LuCaP 86.2. Outcome read from the abstract. View paper

Cite this record

Thadani-Mulero, M., Portella, L., Sun, S., Sung, M., Matov, A., Vessella, R. L., Corey, E., Nanus, D. M., Plymate, S. R., & Giannakakou, P. (2014). Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer. Cancer Research, 74(8), 2270–2282. https://doi.org/10.1158/0008-5472.can-13

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