Diverse somatic mutation patterns and pathway alterations in human cancers

Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, Vasantharajan Janakiraman, Deepali Bhatt, Howard M. Stern, Peng Yue, Peter M. Haverty, Richard Bourgon, Jianbiao Zheng, Martin Moorhead, Subhra Chaudhuri, Lynn P. Tomsho, Brock A. Peters, Kanan Pujara, Shaun Cordes, David P. Davis, Victoria E. H. Carlton, Wenlin Yuan, Li Li, Weiru Wang, Charles Eigenbrot, Joshua S. Kaminker, David A. Eberhard, Paul Waring, Stephan C. Schuster, Zora Modrusan, Zemin Zhang, David Stokoe, Frederic J. de Sauvage, Malek Faham, Somasekar Seshagiri

Nature, 2010. DOI 10.1038/nature09208

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2021.

Replications

Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology, Errington et al. (2021). eLife. Outcome recorded: successful. "To summarize, we found results that were in the same direction as the original study and statistically significant where predicted." Outcome read from the full text. View paper

Cite this record

Kan, Z., Jaiswal, B. S., Stinson, J., Janakiraman, V., Bhatt, D., Stern, H. M., Yue, P., Haverty, P. M., Bourgon, R., Zheng, J., Moorhead, M., Chaudhuri, S., Tomsho, L. P., Peters, B. A., Pujara, K., Cordes, S., Davis, D. P., Carlton, V. E. H., Yuan, W., … Seshagiri, S. (2010). Diverse somatic mutation patterns and pathway alterations in human cancers. Nature, 466(7308), 869–873. https://doi.org/10.1038/nature09208

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