A common variant of HMGA2 is associated with adult and childhood height in the general population

Michael N Weedon, Guillaume Lettre, Rachel M Freathy, Cecilia M Lindgren, Benjamin F Voight, John R B Perry, Katherine S Elliott, Rachel Hackett, Candace Guiducci, Beverley Shields, Eleftheria Zeggini, Hana Lango, Valeriya Lyssenko, Nicholas J Timpson, Noel P Burtt, Nigel W Rayner, Richa Saxena, Kristin Ardlie, Jonathan H Tobias, Andrew R Ness, Susan M Ring, Colin N A Palmer, Andrew D Morris, Leena Peltonen, Veikko Salomaa, George Davey Smith, Leif C Groop, Andrew T Hattersley, Mark I McCarthy, Joel N Hirschhorn, Timothy M Frayling

Nature Genetics, 2007. DOI 10.1038/ng2121

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 successful. The earliest on record is from 2009.

Replications

HMGA2 Is Confirmed To Be Associated with Human Adult Height, Yang et al. (2009). Annals of Human Genetics. Outcome recorded: successful. We confirmed the association between rs1042725 in HMGA2 and adult height both in the unrelated and family‐based Caucasian populations (overall P = 4.25 × 10 −9 ). Outcome read from the abstract. View paper

Cite this record

Weedon, M. N., Lettre, G., Freathy, R. M., Lindgren, C. M., Voight, B. F., Perry, J. R. B., Elliott, K. S., Hackett, R., Guiducci, C., Shields, B., Zeggini, E., Lango, H., Lyssenko, V., Timpson, N. J., Burtt, N. P., Rayner, N. W., Saxena, R., … Frayling, T. M. (2007). A common variant of HMGA2 is associated with adult and childhood height in the general population. Nature Genetics, 39(10), 1245–1250. https://doi.org/10.1038/ng2121

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