A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study

Allard J. Hauer, Sara L. Pulit, Leonard H. van den Berg, Paul I. W. de Bakker, Jan H. Veldink, Ynte M. Ruigrok, Catharina J. M. Klijn, Ale Algra, Ewoud J. van Dijk, Peter J. Koudstaal, Gert-Jan Luijckx, Paul J. Nederkoorn, Robert J. van Oostenbrugge, Marieke C. Visser, Marieke J. Wermer, L. Jaap Kappelle

Scientific Reports, 2017. DOI 10.1038/s41598-017-07404-4

Has this study been replicated?

This paper is itself a replication attempt, targeting 2 studies, listed below.

Studies replicated

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke, Bellenguez et al. (2012). Nature Genetics. View paper
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke, Holliday et al. (2012). Nature Genetics. View paper

Cite this record

Hauer, A. J., Pulit, S. L., van den Berg, L. H., de Bakker, P. I. W., Veldink, J. H., Ruigrok, Y. M., Klijn, C. J. M., Algra, A., van Dijk, E. J., Koudstaal, P. J., Luijckx, G.-J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., & Kappelle, L. J. (2017). A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-07404-4

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