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High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation

Miriam Kesselmeier, Carolin Pütter, Anna-Lena Volckmar, Hansjörg Baurecht, Harald Grallert, Thomas Illig, Khadeeja Ismail, Miina Ollikainen, Yasmina Silén, Anna Keski-Rahkonen, Cynthia M. Bulik, David A. Collier, Eleftheria Zeggini, Johannes Hebebrand, André Scherag, Anke Hinney

The World Journal of Biological Psychiatry, 2016. DOI 10.1080/15622975.2016.1190033

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed. The earliest on record is from 2025.

Replications

• No indications of weight gain associated DNA methylation changes in patients with anorexia nervosa, Rajcsanyi et al. (2025). Scientific Reports. Outcome recorded: failed. no evidence was observed for hypomethylation at the investigated 15 CpG sites of the NR1H3 locus. Outcome read from the abstract. View paper

Cite this record

Kesselmeier, M., Pütter, C., Volckmar, A.-L., Baurecht, H., Grallert, H., Illig, T., Ismail, K., Ollikainen, M., Silén, Y., Keski-Rahkonen, A., Bulik, C. M., Collier, D. A., Zeggini, E., Hebebrand, J., Scherag, A., & Hinney, A. (2016). High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation. The World Journal of Biological Psychiatry, 19(3), 187–199. https://doi.org/10.1080/15622975.2016.1190033

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