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High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation

Miriam Kesselmeier, Carolin Pütter, Anna-Lena Volckmar, Hansjörg Baurecht, Harald Grallert, Thomas Illig, Khadeeja Ismail, Miina Ollikainen, Yasmina Silén, Anna Keski-Rahkonen, Cynthia M. Bulik, David A. Collier, Eleftheria Zeggini, Johannes Hebebrand, André Scherag, Anke Hinney

The World Journal of Biological Psychiatry, 2016. DOI 10.1080/15622975.2016.1190033

Has this study been replicated?

The atlas records 1 replication of this study. Recorded outcomes: 1 failed.

Replications

• No indications of weight gain associated DNA methylation changes in patients with anorexia nervosa, Rajcsanyi et al. (2025). Outcome recorded: failed. no evidence was observed for hypomethylation at the investigated 15 CpG sites of the NR1H3 locus. View paper

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