Nature Genetics

Findings first published in Nature Genetics, paired with the replication and reproduction attempts on record. 23 studies in the atlas.

• Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine Gormley et al., 2016 — 1 mixed
• Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic… Bentham et al., 2015 — 1 mixed
• Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease Steinberg et al., 2015 — 1 mixed
• Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease Lambert et al., 2013 — 2 failed, 1 successful
• Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial… Cordell et al., 2013 — 1 successful
• Seven new loci associated with age-related macular degeneration 2013 — 1 mixed
• Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1 Kirino et al., 2013 — 1 failed
• Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma Vithana et al., 2012 — 1 failed
• A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis Takahashi et al., 2011 — 2 successful
• Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis Sanna et al., 2010 — 1 successful
• A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14 Solouki et al., 2010 — 1 mixed
• New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Dupuis et al., 2010 — 1 mixed
• Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population Takata et al., 2010 — 1 mixed
• Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci 2010 — 1 failed
• Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease Lambert et al., 2009 — 1 mixed
• Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease Satake et al., 2009 — 1 mixed
• Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK… Harley et al., 2008 — 1 failed
• Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus Graham et al., 2007 — 1 successful
• A common variant of HMGA2 is associated with adult and childhood height in the general population Weedon et al., 2007 — 1 successful
• Variation in FTO contributes to childhood obesity and severe adult obesity Dina et al., 2007 — 1 successful
• A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human… Buch et al., 2007 — 1 mixed
• Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes Grant et al., 2006 — 1 successful
• A common variant associated with prostate cancer in European and African populations Amundadottir et al., 2006 — 1 successful